Melanotan-2 (MT-2) is a synthetic derivative of human alpha-melanocyte-stimulating hormone (α-MSH), developed at the University of Arizona in the 1980s. The initial purpose was to create a sunless tanning alternative, inspired by α-MSH’s ability to induce sexual arousal and skin darkening in rodents. However, as research progressed, MT-2’s diverse effects were unveiled. These include enhancing sexual arousal, promoting skin pigmentation, reducing compulsive behavior, managing addiction, suppressing hunger, decreasing glucagon production, and even potentially reversing certain features associated with autism.
Sequence: Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)
Molecular Formula: C50H69N1509
Molecular Weight: 1024.198 g/mol
CAS Number: 121062-08-6
Synonyms: MT2
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